OGI School of Science & Engineering
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Tamara Hayes, Ph.D.

I am a faculty member in the Department of Biomedical Engineering at OHSU. I am affiliated with the Point of Care Laboratory, which serves as the technology research arm of the Oregon Roybal Center for Aging and Technology (ORCATECH). I also have a joint appointment in the Department of Computer Science and Electrical Engineering.
tlh

Research Interests

My research is focused on enabling health assessment and caregiving in the home. With collaborators at ORCATECH and the Point of Care laboratory, I am developing low-cost technologies to allow unobtrusive continuous assessment of cognitive and motor changes. We place sensors in the homes of community-dwelling elders to monitor daily patterns of activity, walking speeds, medication adherence, and other behaviors. These sensors collect continuous data that reflect normal variability in behaviors as well as trends that may indicate problematic changes in cognition or mobility. Because data are collected continuously, trends can be identified long before they would become apparent during a typical clinic visit. However, the use of low-cost sensors means that the data are inherently noisy, and extraction of meaningful behavioral data requires sophisticated statistical and dynamical modeling approaches.

The research has three areas of focus:

  1. Identifying changes in mobility and medication adherence that provide early markers of cognitive and/or motor impairment. These are continuous monitoring studies conducted with seniors living independently in the community.
  2. Development of technology (algorithms and systems) to collect and analyze continuous data from these studies; and
  3. Creation of tools for visualizing the data, to allow identification of reduced data representations of particular interest to elders, their caregivers, and their health professionals.

Teaching

I currently teach two courses:

BME 565/665 Computational Neurophysiology.
This course is offered as part of the neuroengineering track in the Department of Biomedical Engineering, and consequently is offered as new students enter the track.
Last offered Spring 2007: Click here for the syllabus.
CSE 541/641 Database Implementation.
This course was offered annually through the Department of Computer Science and Electrical Engineering.
Last offered Winter 2006. This course is not currently offered by the department. Click here for the syllabus.

Current Projects

Unobtrusive Continuous In-home Assessment
Use of an in-home wireless sensor network to assess early motor and cognitive changes preceding the onset of Alzheimer's disease.
  • Technology/system development: a 16-person cross-sectional pilot study to develop an unobtrusive in-home system for assessing motor activity and cognitive change in the elderly, and to assess differences in activity patterns between healthy seniors and those with Mild Cognitive Impairment. Funded by NIA (P30 AG08017)
  • A longitudinal study of 300 community-dwelling elders, to evaluate the efficacy of the system in predicting early cognitive changes in community-dwelling seniors. Funded by NIA (Bioengineering Research Partnership)
Home-based assessment of cognitive and functional change in the elderly
This study will evaluate the ability of home-based assessments to detect cognitive cognitive change, and will examine medication adherence as a performance-based measure of functional ability. This is a 600 person randomized trial of 3 technologies for assessing cognitive function: mail-in questionnaires, interactive voice response, and computer based assessments. Funded by NIA (through the Alzheimer's Disease Cooperative Study Group)
Behavioral Assessment and Intervention Commons
This is a collaborative research model in which OHSU is partnering with Intel and other academic institutions to create a "commons" of research tools and artifacts relating to behavioral assessment and interventions. The research is focused on technologies to support independent living. The OHSU BAIC has multiple projects involving collaborators in BME, CSEE, Neurology, CSLU, and DMICE.
One of the key components of this research is the Living Lab, a community-based group of volunteers who have agreed to allow us to test technologies in their homes. The homes of these volunteers have been outfitted with numerous sensors (motion sensors, door sensors, RFID tracking devices, bed mats, medication monitors (the MedTracker), and a home computer which is also used as a kiosk for administering automated cognitive tests, as are used in the ADCS study. The Living Lab is used to conduct pilot studies of new technologies, which can be evaluated in the context of a fully-characterized home environment in a population that undergoes regular clinical and neuropsychological testing. Funded by Intel

Completed Projects

Patterns of Medication Adherence
A cross-sectional study of the effect of cognitive loss on medication adherence. This study tracks the activity patterns of 50 elders who are following a prescribed vitamin regimen. The study seeks to identify those patterns of activity leading to missed doses, and to understand the correlation between medication adherence and early memory loss. Funded by NIA (P30 AG024978-02)
A Medication Tracking and Reminding Device
Development of a device for continuous medication monitoring and reminding. The goal of the project is to improve our ability to assess medication adherence during clinical trials and as an activity of daily living. Funded by ORI
Early gait speed changes in Parkinson's Disease
A pilot study to determine if early gait slowing in PD can be detected using unobtrusive in-home sensors. We are monitoring three community-dwelling individuals with early Parkinson's disease to determine if there are detectable gait slowing in the very earliest stages of Parkinson's Disease. Funded by Kinetics Corporation
Tracking multi-person activity in the home
Investigations of technology solutions to the problem of identifying who is moving through an in-home activity monitoring system. The goal of this project is to develop unobtrusive methodologies (algorithmic and technology) for tracking location and activity of multiple people in the same home. Funded by the Oregon Partnership for Alzheimer's Research.
Assessing Sleep and Movement in Bed
Classification of in-bed movements using load cells
PhD Thesis: Adriana Adami, advisors Misha Pavel, Tamara Hayes

Recent Publications

  • Lundell J, Hayes TL, Vurgun S, Ozertem U, Kimel J, Kaye J, Guilak F, Pavel M. Continuous Activity Monitoring and Intelligent Contextual Prompting to Improve Medication Adherence. 29th Annual International Conference of the IEEE Engineering In Medicine and Biology Society, 23-26 August, 2007, Lyon, France.
  • Leen, T, Hayes TL, Zhengdong, L, Kaye JA. Detection of Early Cognitive Loss from Medication. 2nd International Conference on Technology and Aging (ICTA), Proceedings of FICCDAT 2007, 16-19 June, 2007; Toronto, CA.
  • Hayes TL, Pavel M, Kaye JA. Continuous health assessment using in-home sensors. IOS Press, 2007. 2nd International Conference on Technology and Aging (ICTA), Proceedings of FICCDAT 2007, 16-19 June, 2007; Toronto, CA.
  • Pavel M, Hayes TL, Tsay A, Erdogmus W, Paul AS, Larimer N, Jimison H, Nutt J. Continuous Assessment of Gait Velocity in Parkinsons Disease from Unobtrusive Measurements. 3rd International IEEE EMBS Conference on Neural Engineering, 2 5 May 2007, Hawaii, USA.
  • Hayes TL, Pavel M, Adami A, Larimer N, Tsay IA, Nutt J Pervasive Technology in Distributed Healthcare: Simultaneous Assessment of Multiple Individuals. IEEE Pervasive Computing, 2007, 6(1):36-43.
  • Kaye JA , Hayes, TL,. Home Health Monitoring. Generations. 2007
  • Hayes TL, Hunt JM, Adami AG, Kaye J. An electronic pillbox for continuous monitoring of medication adherence. Presented at 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Sep 2006, New York, NY.
  • Pavel M, Hayes TL, Adami AG, Jimison HB, Kaye J. Unobtrusive assessment of mobility. Presented at 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Sep 2006, New York, NY
  • Pavel M, Adami A, M. Morris M, Lundell J, Hayes TL, Jimison H, Kaye JA. Mobility Assessment Using Event-Related Responses. 2006 Transdisciplinary Conference on Distributed Diagnosis and Home Healthcare, 2-4 April, 2006; Arlington, VA.
  • Adami AM, Hayes TL, Pavel M, Singer CM. Detection and Classification of Movements in Bed using Load Cells. 27th Annual International Conference of the IEEE Engineering In Medicine And Biology Society, 1-4 September, 2005; Shanghai, China.
  • Hayes TL, Pavel M, Kaye JA. An Unobtrusive In-home Monitoring System for Detection of Key Motor Changes Preceding Cognitive Decline. 26th Annual International Conference of the IEEE Engineering In Medicine And Biology Society, 1-5 September, 2004; San Francisco, CA.
  • Hayes TL, Pavel M., Schallau PK, Adami AM. Unobtrusive Monitoring of Health Status in an Aging Population. 5th International Conference on Ubiquitous Computing, October 12-15, 2003; Seattle, WA.
  • Adami AM, Hayes TL, Pavel M. Unobtrusive Monitoring of Sleep Patterns. 25th Annual International Conference of the IEEE Engineering In Medicine And Biology Society, 17-21 September, 2003; Cancun, Mexico.