publications

2008

SL Jacques, R Samatham, S Isenhath, K Lee, Polarized light camera to guide surgical excision of skin cancers, SPIE Proceedings, 2008. download

2007

RK Wang, SL Jacques, Z Ma, S Hurst, SR Hanson, A Gruber, Three dimensional optical angiography, Optics Express 2007 (in press)

DS Gareau, G Merlino, C Corless, M Kulesz-Martin, SL Jacques, Noninvasive imaging of melanoma with reflectance mode confocal scanning laser microscopy in a murine model. J Investigative Dermatology (in press 2007)

F Chen, N Choudhury, J Zheng, S Matthews, AL Nuttall, SL Jacques, In vivo imaging and low-coherence interferometry of organ of Corti vibration, J Biomed Optics 041108, 2007.

2006

SL Jacques, Ratio of entropy to enthalpy for thermal transitions in biological tissues. J Biomed Optics, 2006 download

Shangbin Chen, Zhe Feng, Pengcheng Li, Steven L. Jacques, Shaoqun Zeng, Qingming Luo, In vivo optical reflectance imaging of spontaneous spreading depression waves in rat brain with and without focal cerebral ischemia, J Biomed Optics 11(3):034002, 2006 download

Shaoqun Zeng, Xiaohua Lv, Chen Zhan, Wei R. Chen, Wenhui Xiong, Steven L. Jacques, Qingming Luo, Simultaneous Compensation of Both Spatial and Temporal Dispersion of Two-Dimensional Acousto-optical Deflectors in Two-photon Imaging by Use of a Single Prism, Opt Lett (in press), 2006 download

Hillman TR, Adie SG, Seemann V, Armstrong JJ, Jacques SL, Sampson DD. Correlation of static speckle with sample properties in optical coherence tomography. Opt Lett. 31(2):190-2, 2006. download

2005

Gareau DS, Lagowski J, Rossi VM, Viator JA, Merlino G, Kulesz-Martin M, Jacques SL. Imaging melanoma in a murine model using reflectance-mode confocal scanning laser microscopy and polarized light imaging. J Investig Dermatol Symp Proc. 10(2):164-9. 2005 download

Jessica C. Ramella-Roman, Scott A. Prahl, Steven L. Jacques. Three Monte Carlo programs of polarized light transport into scattering media: part II. Optics Express 13(25):10392-10405, 2005 download

Hiroyuki Yoshimura, John A. Viator, Steven L. Jacques, Relationship Between Damaged Fraction and Reflected Spectra of Denaturing Tissues, Lasers Surg. Med. 37:308Ð313, 2005 download

JC Ramella-Roman, SA Prahl, SL Jacques, Three Monte Carlo programs of polarized light transport into scattering media: part I. Optics Express 13(12):4420-4438, 2005. download

PR Bargo, Teresa Goodell RN, Rodger Sleven MD, George Kovall MD, Greg Blair MD, SL Jacques. In vivo determination of optical properties of normal and tumor tissue with white light reflectance and an empirical light transport model during endoscopy. J Biomed Optics 10(3):034018, 2005 download

2004

JC Ramella-Roman, K Lee, SA Prahl, SL Jacques, Design, testing, and clinical studies of a handheld polarized light camera. J Biomed Optics 9(6):1305-1310, 2004. download

DS Gareau, PR Bargo, WA Horton, SL Jacques, Confocal fluorescence spectroscopy of subcutaneous cartilage expressing green fluorescent protein versus cutaneous collagen autofluorescence. J Biomed Optics 9(2):254-258, 2004. download

S.L. Jacques, J.C. Ramella-Roman, Polarized Light imaging of tissues. Ch. 19 in Lasers and Current Optical Techniques in Biology, G. Palumbo, R. Pratesi, eds., Comprehensive series in photochemistry and photobiology Ð Volume 4, publ. The Royal Society of Chemistry, Cambridge, UK, 2004. download

2003

JC Ramella-Roman, SL Jacques, Evaluation of spherical particle sizes with an asymmetric illumination microscope, IEEE J. Selected Topics in Quantum Electronics (in press 2003) download

PR Bargo, SL Jacques, R Sleven, T Goodell, Optical properties effects upon the collection efficiency of multifiber probe configurations, IEEE J. Selected Topics in Quantum Electronics (in press 2003) download

Paulo R. Bargo, Scott A. Prahl, and Steven L. Jacques, Collection efficiency of a single optical fiber in turbid media, Appl. Optics (in press 2003) download

2002

Viator JA, G, Paltauf G, Jacques SL, Prahl SA, Ren H, Chen Z, Nelson JS. Clinical testing of a photoacoustic probe for port wine stain depth determination. Lasers Surg Med. 30(2):141-8, 2002.

Jacques SL, JC Ramella-Roman, K Lee. Imaging skin pathology with polarized light. J Biomed Opt. 7:329-340, 2002. download

Paltauf G, JA Viator, SA Prahl, SL Jacques. Iterative reconstruction algorithm for optoacoustic imaging. J. Acoust. Soc. Am. 112(4):1536-1544, 2002.download

2000

S. L. Jacques, J. Roman, K. Lee: Imaging superficial tissues with polarized light. Lasers Surg. Med. 26:119-129, 2000

V.V. Vaidyanathan, S. Rastegar, T.W. Fossum, P. Flores, E.W. van der Breggan, N.G. Egger, S.L. Jacques, M. Motamedi, A study of aminolevulenic acid-induced protoporphyrin IX fluorescence kinetics in the canine oral cavity. Lasers Surg. Med. 26:405-414, 2000.

S. L. Jacques, N. Ramanujam, G. Vishnoi, R. Choe, B. Chance, Modeling photon transport in transabdominal fetal oximetry. J Biomed Optics 5:277-282, 2000.

1999

J.A. Viator, S.L. Jacques, S.A. Prahl: Depth profiling of absorbing soft materials using photoacoustic methods. IEEE J. Selected Topics in Quantum Electronics 5:989-996, 1999.

1998

S. L. Jacques: Light distributions from point, line, and plane sources for photochemical reactions and fluorescence in turbid biological tissues. Photochem. Photobiol. 67:23-32, 1998. download

S. L. Jacques: Light distributions from point, line, and plane sources for photochemical reactions and fluorescence in turbid biological tissues. Photochem. Photobiol. 67:23-32, 1998.

S. L. Jacques, S. J. Kirkpatrick: Acoustically modulated speckle imaging of biological tissues. Optics Letters, 23:879-881, 1998.

1997

A.A. Oraevsky, S.L. Jacques, F.K. Tittel: Measurement of tissue optical properties by time-resolved detection of laser-induced transient stress. Applied Optics 36:402-415,1997.

M.R. Ostermeyer, S.L. Jacques: Perturbation theory for diffuse light transport in complex biological tissues. J. Opt. Soc. Am. A 14:, 1997.

S.-P. Lin, L.-H. Wang, S. L. Jacques, and F. K. Tittel: Measurement of tissue optical properties using oblique incidence optical fiber reflectometry, Applied Optics, 36, 136-143, 1997.

L. Wang, S. L. Jacques, L. Zheng: CONV - convolution for responses to a finite diameter photon beam incident on multi-layered tissues. Computer Methods and Programs in Biomedicine 54:141-150, 1997.

Chung YG; Schwartz JA; Gardner CM; Sawaya RE; Jacques SL, Diagnostic potential of laser-induced autofluorescence emission in brain tissue. J Korean Med Sci 12:2, 135-42, 1997.

R.A. London, M.E. Glinsky, G.B. Zimmerman, D.S. Bailey, D.C. Eder, S.L. Jacques, Laser-tissue interactions modeling with LATIS. Applied Optics 36:9068-9074, 1997.

1996

C.M. Gardner, S.L. Jacques, A.J. Welch: Light transport in tissue: Accurate expressions for one-dimensional fluence rate and escape function based upon monte carlo simulation, Lasers Surg Med. 18(2):129-38, 1996.

A.A. Oraevsky, S.L. Jacques, R.O. Esenaliev, F.K. Tittel: Pulsed laser ablation of soft tissues, gels, and aqueous solutions at temperatures below 100 ¡C. Lasers in Surgery and Medicine 18:231-240, 1996

B-M. Kim, S.L. Jacques, S. Rastegar, S. Thomsen, M. Motamedi. Nonlinear finite-element analysis of the role of dynamic changes in blood perfusion and optical properties in laser coagulation of tissue. IEEE J Selected Topics in Quantum Electronics 2:922-933, 1996

Thompson CR; Gerstman BS; Jacques SL; Rogers ME, Melanin granule model for laser-induced thermal damage in the retina. Bull Math Biol 58:3, 513-53, 1996.

Glenn TN; Rastegar S; Jacques SL, Finite element analysis of temperature controlled coagulation in laser irradiated tissue. IEEE Trans Biomed Eng 43:1, 79-87, 1996.

A.H. Hielscher, H. Liu, B. Chance, F.K. Tittel, S.L. Jacques: Time-resolved photon emission from layered turbid media. Appl. Opt. 35:719-728, 1996.

1995

Gostout C.J., S.L. Jacques: Infrared video imaging of subsurface vessels: a feasibility study for the endoscopic management of gastrointestinal bleeding. Gastrointestinal Endoscopy 41:218-224, 1995.

L.-H. Wang, S. L. Jacques, X. Zhao: Continuous-wave ultrasonic modulation of scattered laser light to image objects in turbid media. Optics Letters 20:629-631, 1995.

L.-H. Wang, S. L. Jacques: Use of a laser beam with an oblique angle of incidence to measure the reduced scattering coefficient of a turbid medium. Applied Optics, 34:2362-2366, 1995.

L.-H. Wang, S. L. Jacques, L.-Q. Zheng: MCML - Monte Carlo modeling of photon transport in multi-layered tissues. Computer Methods and Programs in Biomedicine, 47, 131-146, 1995.

Nelson JS. Milner TE. Anvari B. Tanenbaum BS. Kimel S. Svaasand LO. Jacques SL:Dynamic epidermal cooling during pulsed laser treatment of port-wine stain. A new methodology with preliminary clinical evaluation. Archives of Dermatology 131(6):695-700, 1995

Sterenborg NJ. Thomsen S. Jacques SL. Duvic M. Motamedi M. Wagner RF Jr.: In vivo fluorescence spectroscopy and imaging of human skin tumors. [letter] Dermatologic Surgery 21(9):821-2, 1995

H. Liu, A.H. Hielscher, S.L. Jacques, F.K. Tittel, B. Chance: Influence of blood vessels on the measurement of hemoglobin oxygenation as determined by time-resolved reflectance spectroscopy. Med Phys 22:1209-1217, 1995.

A.H. Hielscher, S.L. Jacques, L.H. Wang, F.K. Tittel: Influence of boundary conditions on the accuracy of diffusion theory in time-resolved reflectance spectroscopy of biological tissues. Phys. Med. Biol. 40:1-19, 1995.

I.S. Saidi, S.L. Jacques, F.K. Tittel: Mie and Rayleigh modeling of visible-light scattering in neonatal skin. Appl. Opt. 34:7410-7418, 1995.

A.A. Oraevsky, S.L. Jacques, F.K. Tittel: Mechanism of laser ablation for aqueous media irradiated under confined stress conditions. J Appl Phys 78:1281-1290, 1995

1994

He X-Y., R.A. Sikes, S. Thomsen, L.W.K. Chung, S.L. Jacques: Photodynamic therapy with Photofrin II induces programmed cell death in carcinoma cell lines. Photochem. Photobiol. 59:468-473, 1994.

Wang L.-H., S.L. Jacques: Optimized radial and angular positions in Monte Carlo modeling. Med. Phys. 21:1081-1083, 1994.

H.J.C.M. Sterenborg, M. Motamedi, R.F. Wagner Jr., S. Thomsen, S.L. Jacques: In vivo fluorescence spectroscopy and imaging of human skin tumors. Lasers in Medical Science 9:191-201, 1994.

L. Wang, S.L. Jacques: Error estimation of measuring total interaction coefficients of turbid media using collimated light transmission. Phys. Med. Biol. 39:2349-2354, 1994.

1993

Oraevsky, A., S.L. Jacques, G.H. Pettit, R.A. Sauerbrey, F.K. Tittel, J.H. Nguy, P.D. Henry: XeCl laser induced fluorescence of atherosclerotic arteries: spectral simlarities between fatty lesions and peroxidized lipoproteins. Circulation 72:84-90, 1993.

Jacques, S.L., J.S. Nelson, W.H. Wright: Pulsed photothermal radiometry of portwine stain lesions. Applied Optics 32:2439-2446, 1993.

Jacques, S.L.: The role of tissue optics and pulse duration during high-power laser irradiation. Applied Optics 32:2447-2454, 1993.

Oraevsky, A., G.H. Pettit, S.L. Jacques, R.A. Sauerbrey, F.K.Tittel, P.D. Henry: XeCl laser ablation of atherosclerotic aorta: luminescence spectroscopy of ablation products. Lasers Surg. Med. 13:168-178, 1993.

Lynn C.J., I.S. Saidi, D.G. Oelberg, S.L. Jacques: Gestational age correlates with skin reflectance in newborn infants of 24-42 weeks gestation. Biology of the Neonate 64:69-75, 1993.

Wang L.-H., S.L. Jacques: Hybrid model of Monte Carlo simulation and diffusion theory for light reflectance by turbid media. J. Opt. Soc. Am. A 10:1746-1752, 1993.

Stern S.J., J. Craig, S. Flock, D. Montague, M. Waner, S. Jacques: Tumor specific response to photodynamic therapy. Lasers Surg. Med. 13:434-439, 1993.

Lilge L., T.J. Flotte, I.E. Kochevar, S.L. Jacques, F. Hillenkamp: Photoactivatable fluorophores for the measurement of fluence in turbid media. Photochem. Photobiol. 58:37-44, 1993.

Flock S.T., S.L. Jacques: Thermal damage of blood vessels in a rat skin-flap window chamber using indocyanine green and a pulsed alexandrite laser: A feasibility study. Lasers in Medical Science 8:185-196, 1993.40.

1992

Jacques SL: Laser-tissue interactions: photochemical, photothermal, and photomechanical. Surgical Clinics, 72:531-558, 1992. download (10.6 MB)

Madsen, S.J., B.C. Wilson, M.S. Patterson, Y.D. Park, SL Jacques,.Y. Hefetz: Experimental tests of a simple diffusion model for the estimation of scattering and absorption coefficients of turbid media from time-resolved diffuse reflectance measurements. Applied Optics 31:3509-3517, 1992

Flock, S.T., S.L. Jacques, B.C. Wilson, W.M. Star, M.J.C. van Gemert: Optical properties of intralipid: a phantom medium for light propagation studies. Lasers Surg. Med. 12:510-519, 1992.

Oraevsky, A., S.L. Jacques, G.H. Petit, I.S. Saidi, R.A. Sauerbrey, F.K. Tittel, P.D. Henry: XeCl laser ablation of atherosclerotic aorta: optical properties and energy pathways. Lasers Surg. Med. 12:585-597, 1992.

1991

Jacques SL, DJ McAuliffe: The melanosome: threshold temperature for explosive vaporization and internal absorption coefficient during pulsed laser irradiation. Photochem Photobiol 53:769-776, 1991

Stern, S. J., S. Flock, S. Small, S. L. Thomsen and S. L. Jacques: An Implantable Tumor-Window Chamber Model for the Study of Photodynamic Therapy. Otolaryngology - Head and Neck Surgery 105:556-566, 1991.

Stern, S. J., S. Flock, S. Small, S. L. Thomsen and S. L. Jacques: Chloroaluminum sulfonated phthalocynanine versus dihematoporphyrin ether: Early vascular events in the rat window chamber. Laryngoscope 101:1219-1225, 1991.

Yashima Y, DJ McAuliffe, SL Jacques, TJ Flotte: Laser induced photoacoustic injury of skin: effect of inertial confinement. Lasers in Surgery and Medicine 11(1):62-68, 1991.

Nelson, JS, JL McCullough, TC Glenn, WH Wright, LL Liaw, SL Jacques: Mid-infrared laser ablation of stratum corneum enhances in vitro percutaneous transport of drugs. J Invest. Dermatol. 97:874-879, 1991.

1990

Rosen CF, SL Jacques, ME Stuart, RW Gange: Immediate pigment darkening: Visual and reflectance spectrophotometric analysis of the action spectrum. Photobiol Photochem 5:583-588, 1990

Wilson BC, Jacques SL: Optical reflectance and transmittance of tissues: principles and applications. IEEE J Quantum Electronics, 26:2186-2199, 1990

Stern SJ, SL Thomsen, S Small, SL Jacques: Photodynamic therapy with chloroaluminum sulfonated phthalocyanine (CASP). Archives of Otolaryngology, Head and Neck Surgery 116:1259-1266, 1990

Stern SJ, ST Flock, S Small, SL Thomsen, SL Jacques: Photodynamic therapy with chloroaluminum sulfonated phthalocynanine (CASP) in the rat window chamber. Am. J. Surg., 160:360-364, 1990

1989

Granstein RD, MR Deak, SL Jacques, RJ Margolis, TJ Flotte, D Whitaker, FH Long, EP Amento: The systemic administration of gamma interferon inhibits collagen synthesis and acute inflammation in a murine skin wounding model. J Invest Dermatol 93:18-27, 1989

Keijzer M, SL Jacques, SA Prahl, AJ Welch: Light distributions in artery tissue: Monte Carlo simulations for finite-diameter laser beams. Lasers Surg.Med. 9:148-154, 1989

Anderson RR, H Beck, U Bruggemann W Farinelli, SL Jacques, JA Parrish: Pulsed photothermal radiometry in turbid media: internal reflection of back-scattered radiation strongly influences optical dosimetry. Applied Optics 28:2256-2262, 1989

Parsa P, SL Jacques, N Nishioka: Optical properties of the liver. Applied Optics 28:2325-2330, 1989

Jacques SL: Time-resolved propagation of ultra-short laser pulses within turbid tissues. Applied Optics 28:2223-2229, 1989

Keijzer M, R Richards-Kortum, SL Jacques, MS Feld: Fluorescence spectroscopy of turbid media: autofluorescence of the human aorta. Applied Optics 28:4286-4292, 1989

Jacques SL: Time-resolved reflectance spectroscopy in turbid tissues. IEEE Transactions in Biomedical Engineering, 36:1155-1161, 1989.

van Gemert MJC, SL Jacques, HJCM Sterenborg, WM Star: Skin Optics. IEEE Transactions in Biomedical Engineering, 36:1146-1154, 1989.

Jacques SL: Simple theory, measurements, and rulse of thumb for dosimetry during photodynamic therapy. SPIE 1065:100-108, 1989. download

1988

Nishioka NS, SL Jacques, JM Richter, RR Anderson: Reflection and transmission of light from the esophagus: The influence of incident angle. Gasteroenterology 94:1180-1185, 1988

Watanabe S, TJ Flotte, DJ McAuliffe, SL Jacques: Putative photoacoustic damage in skin induced by pulsed ArF excimer laser. J Invest Dermatol 90:761-766, 1988

1987

Polla, L.L., S. L. Jacques, R. J. Margolis, M. R. Prince, R. R. Anderson, J. A. Parrish, O.T. Tan: Photothermolyse selective: Application au traitement des angiomes plans parle laser. Ann. Dermatol. Venereol. 114:497-506, 1987.

Jacques, S. L., D. J. McAuliffe, I. H. Blank, J. A. Parrish: Controlled removal of human stratum corneum by pulsed laser. J. Invest. Dermatol. 88:88-93, 1987.

Jacques, S. L., S. A. Prahl: Modeling optical and thermal distributions in tissue during laser irradiation. Lasers in Surg. Med. 6:494-503, 1987.

Jacques, S. L., D. R. Weaver, S. M. Reppert: Penetration of light into the uterus of pregnant mammals. Photochemistry and Photobiology 45:637-641, 1987.

Polla LL, RJ Margolis, JS Dover, D Whitaker, GF Murphy, SL Jacques, RR Anderson: Melanosomes are a primary target of Q-switched ruby laser irradiation in guinea pig skin. J Invest Dermatol 89:281-286, 1987

Jacques SL, CA Alter, SA Prahl: Angular dependence of HeNe laser light scattering by human dermis. Lasers in the Life Sciences 1:309-334, 1987

1985

PhD Dissertation Thesis:
Water content and concentration profile in human stratum corneum, Univ. of California, Berkeley, publ. University Microfilms International, 1985.

1981

Jacques, S., Z. R. Sung: Regulation of pyrimidine and arginine biosynthesis investigated by the use of phaseolotoxin and 5-fluorouracil. Plant Physiology 67:287-291, 1981.

1980

Sung, Z. R., S. Jacques: 5-Fluorouracil resistance in carrot cell cultures: Its use in studying the interaction of pyrimidine and arginine pathways. Planta 148:389-396, 1980.

Book Chapters

1. van Gemert, M. J. C., A. J. Welch, S. L. Jacques, W. F. Cheong, W. M. Star: Light distribution, optical properties, and cardiovascular tissues. In Lasers in Cardiovascular Medicine and Surgery: Fundamentals and Techniques, ed. G. S. Abela, Boston: Kluwer Academic Publishers, 1990, pg. 93-110.

2. Jacques S. L.: The role of skin optics in diagnostic and therapeutic uses of lasers. In Lasers in Dermatology, R. Steiner, editor, Berlin: Springer-Verlag, publisher, p. 1-21, 1991.

3. Jacques S. L.: The ArF excimer laser in dermatology. In Lasers in Dermatology, R. Steiner, editor, Berlin: Springer-Verlag, publisher, p. 116-129, 1991.

4. Jacques S.L., L. Wang: Monte Carlo modeling of light transport in tissues. In Optical Thermal Response of Laser Irradiated Tissue, eds. A.J. Welch, M.J.C. van Gemert. Plenum Publishing Corp., New York (in press).

5. Jacques S.L., L. Wang, A. Hielscher: Time-resolved photon propagation in tissues.. In Optical Thermal Response of Laser Irradiated Tissue, eds. A.J. Welch, M.J.C. van Gemert. Plenum Publishing Corp., New York (in press).

6. Jacques S., A. Gutsche, J. Schwartz, L. Wang, F. Tittel: Video reflectometry to extract optical properties of tissue in vivo. In SPIE Institutes "Optical Medical Tomography: Functional Imaging and Monitoring", ed. G. MŸller, Vol. IS11, SPIE Press, Bellingham, WA, USA, 1993.

7. Jacques S.L.: Path integral description of light transport in tissue. Ann NY Acad Sci 838:1-13, "Optical Mammography", ed. R. Alfano, 1998.