C. J. M. Moes, M. J. C. van Gemert, W. M. Star, J. P. A. Marijnissen, S. A. Prahl, Appl. Opt., 28, 2292-2296 (1989).
We have studied the influence of absorption, scattering, and refractive index of a phantom medium in conjunction with various beam diameters on the penetration depth of light at 633 nm. We used mixtures of Intralipid 10% (scattering medium) and Evans blue (absorbing medium). Measurements were performed in media with a scattering coefficient of 1/mm, an anisotropy factor of 0.71, absorption coefficients of 0.0013, 0.01, and 0.05/mm, and a refractive index of 1.33. The experimental results were compared with an analytical solution of the fluence rate based on diffusion theory. We found good agreement (deviations of < 10%) between theory and experiment for incident beam diameters between 10 and 60 mm.
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