H. Xie, L. A. Buckley, S. A. Prahl, B. S. Schafer, K. W. Gregory, SPIE Proceedings of Lasers in Surgery: Advanced Characterization, Therapeutics and Systems XI, 4244, 189-192 (2001).

Successful laser-assisted tissue welding was implemented to provide proper weld strength with minimized tissue thermal injury. We investigated and compared the weld strengths and morphologic changes in porcine small intestinal submucose (SIS) and porcine ureteral tissues with various concentration of indocyanine green (ICG) and with a solid albumin sheet. The study showed that the tissues were welded at lower ICG concentration (0.05 mM) with minimized tissue thermal damage using an 800 nm wavelength diode laser.

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